http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009126589-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N55-02 |
| filingDate | 2007-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009126589-A |
| titleOfInvention | COMPOSITIONS, SYNTHESIS AND METHODS OF APPLICATION OF CHOLINESTERASE INHIBITORS BASED ON INDANON |
| abstract | 1. Derived indanone structural formula (I)! ! or a pharmaceutically acceptable salt, hydrate or solvate thereof, wherein the derivative contains a “flexible” moiety conjugated directly or via a spacer to one of the substituents R1, R2, R3, R4, R5 or R6, where! A and D are independently selected from CH or N; ! B represents - (CH2) n-, - (CH2) nC (O) -, - (CH2) nC (O) O-, - (CH2) nOC (O) -, - (CH2) nS (O) ( O) -, - (CH2) nNHC (O) -, O, S, -C (O), -C (O) O or -S (O) (O), where n can be an integer from 1 to 5 ; and! R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cycloheteroalkyl, heteroaryl, substituted heteroarylalkyl, substituted heteroarylalkyl, acylalkyloxycarbonyl, acyloxyalkyloxycarbonyl, acylalkyloxycarbonylamino, acyloxyalkyloxycarbonylamino, alkoxy, alkoxycarbonyl, alkoxycarbonylalkoxy, alkoxycarbonylalkylamino nyl, alkylsulfonyl, alkylthio, amino, alkylamino, arylalkylamino, dialkylamino, arylalkoxy, arylalkoxycarbonylalkylamino, aryloxycarbonyl, aryloxycarbonylalkylamino, aryloxycarbonylaminoamino, sulfonamide, where R1 and R2, R2 and R3 or R4 and R5 may optionally form a 5- or 6-membered ring. ! 2. The derivative of claim 1, wherein the “flexible” part is an amide, ester, carbonate, phosphate, sulfate, or carbamate. ! 3. The derivative of claim 2, wherein the “flexible” part further comprises a spacer. ! 4. The derivative of claim 3, � |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2605931-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9637454-B2 |
| priorityDate | 2006-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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