http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009126418-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 |
| filingDate | 2007-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009126418-A |
| titleOfInvention | METHOD FOR PREVENTION OR TREATMENT OF MYOCARDIAL ISCHEMIA |
| abstract | 1. A method for preventing, slowing down or treating a disease or condition known as myocardial ischemia, which consists in administering to a warm-blooded animal in need of such treatment a therapeutically effective amount of a DGAT1 inhibitor. ! 2. The method according to claim 1, where the warm-blooded animal is a human being. ! 3. The use of a DGAT1 inhibitor to obtain a pharmaceutical composition for treating a subject with a disorder or disease known as myocardial ischemia, which is treatable by inhibiting DGAT1. ! 4. The use according to claim 3, where the DGAT1 inhibitor is a compound that is characterized by the following structure! A-L1-B-C-D-L2-E,! and its pharmaceutically acceptable salts and prodrugs,! where A is substituted or unsubstituted alkyl, cycloalkyl, aryl or heterocyclyl! L1 is selected from the group consisting of! Amino group -NH-,! a substituted amino group of the formula —N (CH 3) -, —CH 2 —NH— or —CH 2 —CH 2 —NH—,! the amido group —C (O) —NH—,! sulfonamido group -S (O) 2-NH- or! urea -NHC (O) -NH-,! B means a substituted or unsubstituted, monocyclic, 5- or 6-membered divalent heteroaryl group,! C-D is selected from the following cyclic structures! C-D together means a substituted or unsubstituted divalent biphenyl group,! C means a substituted or unsubstituted divalent phenyl group, a D means a single bond,! C is a substituted or unsubstituted divalent phenyl group, and D is a substituted or unsubstituted divalent non-aromatic monocyclic ring selected from saturated or unsaturated divalent cycloalkyl groups or from saturated or unsaturated divalent g |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2612556-C2 |
| priorityDate | 2006-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.