http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009123440-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C265-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-96 |
| filingDate | 2007-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009123440-A |
| titleOfInvention | METHOD FOR PRODUCING Phenylalanine Derivatives with Quinazolinedione Skeleton and Intermediates Used in the Preparation of Such Derivatives |
| abstract | 1. A method of obtaining a phenylalanine derivative with a quinazolinedione ring represented by the following formula (1), or a pharmaceutically acceptable salt thereof, comprising the following steps (a), (b) and (c)! ! where R1 represents either a phenyl group which may contain a substituent or a pyridyl group which may contain a substituent; R2 represents an alkyl group which may contain a substituent; R3 represents an alkyl group substituted by a dialkylamino group, an alkyl group substituted by a monoalkylamino group, or an alkyl group substituted by an amino group; and R4 represents a hydrogen atom, an alkyl group or a benzyl group which may contain a substituent; ! (a) the interaction of the acylphenylalanine derivative represented by the following formula (2), or a chemically acceptable salt thereof! ! where R1 and R2 have the same meanings as above,! with a reagent introducing a carbonyl group and a derivative of anthranilic acid represented by the following formula (3), or a chemically acceptable salt thereof! ! where R3 'represents an alkyl group substituted by a dialkylamino group, an alkyl group substituted by a monoalkylamino group which may have a protecting group, or an alkyl group substituted by an amino group which may have a protecting group,! with the formation of a urea derivative with asymmetrically located carboxy groups represented by the following formula (4), or a chemically acceptable salt thereof! ! where R1, R2 and R3 'have the same meanings as indicated above; ! (b) conversion of an urea derivative with an asymmetrically arranged carboxy group� |
| priorityDate | 2006-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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