http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009121014-A
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate | 2009-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2010-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2009121014-A |
titleOfInvention | METHOD FOR DETERMINING ANTIOXIDANT ACTIVITY OF SUBSTANCE |
abstract | A method for determining the antioxidant activity of a substance, including the introduction of the substance being evaluated into the body of experimental animals, slaughter of experimental and control animals, preparation of biological products from the tissues and organs of both groups of animals, and the identification and quantification of metabolic indicator substances in the body of these animals, characterized in that the introduction of the evaluated substance into the body of experimental animals is performed by inhalation, while the content of peroxidation products is determined in both groups pids and natural antioxidants in lung tissue, in blood plasma, in red blood cells and platelets, which are converted into points, and summarized by the expression: Paa = L + Kp + E + T,! where Paa - an indicator of the antioxidant activity of the substance, score (from 0 to 4); L - indicator reflecting the content of lipid peroxidation products and natural antioxidants in lung tissue score; Kp - an indicator reflecting the content of lipid peroxidation products and natural antioxidants in blood plasma, score; E - an indicator reflecting the content of lipid peroxidation products and natural antioxidants in red blood cells, score; T is an indicator reflecting the content of lipid peroxidation products and natural antioxidants in platelets, a score, in addition, a higher value of the sum of points corresponds to a greater antioxidant activity of the substance, while the antioxidant activity of the substance is evaluated relative to the normal values of the content of lipid peroxidation products and natural antioxidants (N), which are defined as the arithmetic mean |
priorityDate | 2009-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.