http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009117388-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81 |
| filingDate | 2007-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009117388-A |
| titleOfInvention | 4- [4 - ({[4-Chloro-3- (trifluoromethyl) phenyl] carbamoyl} monohydrate}) amino) -3-fluorophenoxy] -N-methylpyridine-2-carboxamide |
| abstract | 1. The compound of formula (II)! ! 2. The compound according to claim 1, which shows a maximum peak angle of 2 theta 21.2 with x-ray diffractometry. ! 3. The compound according to claim 1, which shows in the far infrared spectrum a peak maximum value of 353 cm -1. ! 4. The method of obtaining the compounds of formula (II) according to any one of claims 1 to 3, comprising dissolving 4- [4 - ({[4-chloro-3- (trifluoromethyl) phenyl] carbamoyl) amino) -3-fluorophenoxy] -N -methylpyridin-2-carboxamide and adding water to precipitate. ! 5. A method of obtaining a compound of formula (II) according to any one of claims 1 to 3, comprising suspending 4- [4 - ({[4-chloro-3- (trifluoromethyl) phenyl] carbamoyl} amino) -3-fluorophenoxy] -N methyl pyridine-2-carboxamide in an aqueous solvent, and then stirring or shaking until conversion to the compound of formula (II). ! 6. The compound of formula (II) according to any one of claims 1 to 3 for the treatment of giperproliferative diseases. ! 7. The compound of formula (II) according to any one of claims 1 to 3 for the treatment of solid tumors, lymphomas, sarcomas, leukemias, breast cancers, respiratory tract, brain, reproductive organs, digestive tract, urinary tract, eye, liver, skin, head and neck, thyroid and / or parathyroid gland. ! 8. The use of the compounds of formula (II) according to any one of claims 1 to 3 to obtain a pharmaceutical composition for the treatment of hyperproliferative diseases. ! 9. The use of claim 8 for the treatment of solid tumors, lymphomas, sarcomas, leukemias, cancers of the breast, respiratory tract, brain, reproductive organs, digestive tract, urinary tract, eye, liver, skin, head and neck, thyroid and / or parathyroid gland. ! 10. A pharmaceutical composition comprising mainly a compound of formula (II) according to any and |
| priorityDate | 2006-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.