http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009111194-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-06 |
| filingDate | 2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009111194-A |
| titleOfInvention | METHOD FOR PRODUCING L-AMINO ACIDS |
| abstract | 1. The method of obtaining L-amino acids, including! (A) growing bacteria of the Enterobacteriaceae family capable of production! L-amino acid in a nutrient medium containing xylose, and! (B) and the isolation of L-amino acids from the culture fluid,! characterized in that the bacterium is modified in such a way that the activity of ribonuclease G. is reduced in it! 2. The method according to claim 1, characterized in that the rng gene encoding ribonuclease G is inactivated. ! 3. The method according to claim 2, characterized in that the rng gene contains DNA encoding the amino acid sequence of SEQ ID NO: 2, or a variant thereof. ! 4. The method according to claim 1, characterized in that the aforementioned bacterium is additionally modified so that it increases the activity of D-xylose permease. ! 5. The method according to claim 1, characterized in that the aforementioned bacterium is further modified so that the expression of the xylABCFGHR operon is increased in it. ! 6. The method according to claim 1, characterized in that the aforementioned bacterium is further modified in such a way that xylose isomerase activity is increased in it. ! 7. The method according to claim 1, characterized in that the L-amino acid is selected from the group consisting of L-lysine, L-glutamic acid, L-threonine, L-arginine, L-histidine, L-isoleucine, L-valine, L -leucine, L-phenylalanine, L-tyrosine, L-tryptophan, L-proline, L-cysteine, and combinations thereof. ! 8. The method according to claim 1, characterized in that the L-amino acid is L-lysine, and the activity of enzymes selected from the group consisting of dihydrodipicolinate reductase, diaminopimelate dehydrogenase, phosphoenolopyruvate carboxylase, aspartate aminotransferase, aspartate aminotransferase |
| priorityDate | 2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 974.