http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009110098-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-02 |
| filingDate | 2007-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009110098-A |
| titleOfInvention | COMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF Bcl PROTEINS WITH BINDING PARTNERS |
| abstract | 1. The compound of formula 1! ! or a pharmaceutically acceptable salt thereof,! where in each case independently of each other! m is 0, 1, 2 or 3,! n, o and p in each case are independently 1, 2, 3, 4 or 5,! R1 is —OH, —OC (O) R6, —OC (O) N (R6) (R7) or —N (R6) (R7),! R2 is —OH, —N (R8) (R9), —N (R) C (O) N (R8) (R9) or —N (R) C (O) R10, or a group of formula 1b,! ! R3 is alkyl, halogen, alkoxy, (cycloalkyl) alkoxy, aralkyloxy or —O (CH2) 2-N (R15) (R16),! R4 is alkyl, alkoxy, hydroxyalkyl, alkoxyalkyl, halogen, nitro, amino, acyl, amido, acylamino, aminoalkyl, acylaminoalkyl, acylaminoalkylamino, sulfonylaminoalkylamino, carboxylate or —N = C (N (R) 2) 2,! R5 means —OH or —N (R17) (R18),! R6 and R7 independently in each case mean H, alkyl, aralkyl, heteroaralkyl or - [C (R15) (R16)] n-R19,! R8 and R9 independently in each case mean H, alkyl, aralkyl or heteroaralkyl! R10 is alkyl, haloalkyl or - [C (R15) (R16)] o-COOR,! R, R11, R12, R13, R14, R15 and R16 independently in each case mean H or alkyl,! R17 and R18 independently in each case mean H, alkyl, aralkyl, heteroaralkyl, alkoxy or - [C (R19) (R20)] p-R21,! R19 and R20 independently in each case mean H, hydroxy, alkyl, alkoxy, amino, aminoalkyl, acylamino, sulfonylamino, aryl, aralkyl, cycloalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl or heteroarakyl,! R21 independently in each case means H, alkyl, aryl, heteroaryl, heterocyclyl, heterocyclylalkyl, alkoxy, alkylsulfonyl, arylsulfonyl, alkylsulfonamido, arylsulfonamido, amino, amido or carboxyl,! R22 independently in each case means halogen or alkyl,! R23 is selected from the group consisting of alkyl, hydroxyalkyl, alkoxyalkyl, acyloxyalkyl and haloalkyl,! R24 is selected from the group consisting of alkyl, hydroxyalkyl, alk� |
| priorityDate | 2006-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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