http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009109248-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 |
| filingDate | 2006-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009109248-A |
| titleOfInvention | ONCOLOGICAL SENSITIZER CONTAINING Glucosamine, Glucosamine Derivatives, or Their Salts |
| abstract | 1. Oncological sensitizer containing glucosamine, a derivative of glucosamine or their salt. ! 2. The oncological sensitizer according to claim 1, where the glucosamine derivative is represented by the following formula 2:! formula 2! ! where R represents an acyl group having 2-18 carbon atoms, or a straight or branched chain alkyl group having 1-5 carbon atoms. ! 3. The oncological sensitizer according to claim 1, where the oncological sensitizer inhibits the chemoresistance of cancer cells. ! 4. The oncological sensitizer according to claim 1, where the salt is sulfate. ! 5. A composition for inhibiting chemoresistance containing glucosamine, a glucosamine derivative or a salt thereof, and a pharmaceutically acceptable carrier. ! 6. An anti-cancer composition containing the composition according to claim 5 and an anti-cancer agent. ! 7. The anticancer composition according to claim 6, wherein the anticancer agent is selected from the group consisting of mechlorethamine, chlorambucil, phenylalanine, mustard gas, cyclophosphamide, ifosfamide, carmustine (BCNU), lomustine (CCNU), streptozotocin, busulfan, thiotepin, carbisplat, cisp dactinomycin (actinomycin D), doxorubicin (adriamycin), daunorubicin, idarubicin, mitoxantrone, plicamycin, mitomycin, bleomycin C, vincristine, vinblastine, paclitaxel, docetaxel, etoposide, teniposide and topotecan. ! 8. A method of weakening chemoresistance, including the introduction of an oncological sensitizer according to claim 1 or a composition according to claim 5. ! 9. The composition of claim 5, wherein the salt is sulfate. ! 10. The anti-cancer composition according to claim 6 or 7, where the salt is sulfate. ! 11. The method of claim 8, where the salt is sulfate. |
| priorityDate | 2006-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.