http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009105179-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
filingDate | 2007-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2010-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2009105179-A |
titleOfInvention | SULFONILAMINOCARBONYL DERIVATIVES OF CHOLIC ACID AMIDES FOR APPLICATION AS IMMUNOMODULATORS |
abstract | 1. Amides of 4- (3-hydroxy-10,13-dimethylhexadecahydrocyclopenta [a] phenanthren-17-yl) pentanoic acid, where the nitrogen atom in the amide group is replaced by a sulfonylaminocarbonyl (C1-C4) alkyl group. ! 2. The compound according to claim 1 of the formula! ! where R means! (C5-C8) branched chain alkyl,! (C1-C4) alkyl, substituted with groups (C3-C18) cycloalkyl, (C6-C18) aryl or heterocyclyl, optionally including fused rings containing from 3 to 18 atoms in the cycle and from 1 to 8 heteroatoms selected from N, Oh or S,! halogen (C1-C4) alkyl, such as CF3,! (C3-C18) cycloalkyl,! (C6-C18) aryl, or! heterocyclyl, optionally including fused rings containing from 3 to 18 atoms in the cycle and from 1 to 8 heteroatoms selected from N, O or S, and! n is from 1 to 4,! where cycloalkyl, aryl or heterocyclyl are unsubstituted or substituted by halogen, (C1-C8) alkyl, halogen (C1-C4) alkyl, oxo, hydroxy, (C1-C8) alkoxy, (C6-C12) aryloxy, heterocyclyloxy, cyano, carboxy, (C1-C13) acyl, amino, nitro, SO3H or sulfonylamino! where heterocyclyl optionally includes fused rings containing from 3 to 18 atm ring and from 1 to 8 heteroatoms that are selected from N, O or S.! 3. The compound of formula I according to claim 2, where! R means! phenylmethyl! CF3,! unsubstituted or substituted phenyl or naphthyl substituted with one or more methoxy, methylcarbonyloxy, dimethylamino, CF3 groups, halogen, such chlorine, fluorine, or aromatic heterocyclyl containing 5 or 6 atoms in the ring! unsubstituted or substituted aromatic heterocyclyl or aromatic heterocyclyl substituted with one or more methoxy, methylcarbonyloxy, dimethylamino, CF3, halogen or oxo groups, and n is 1 or 2.! 4. Connection |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2689335-C1 |
priorityDate | 2006-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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