| abstract |
1. The compound having the formula! ! where R represents a substituted or unsubstituted thiazolyl group having the formula! ! R4 and R5, each independently selected from! i) hydrogen; ! ii) substituted or unsubstituted C1-C6 linear, branched or cyclic alkyl; ! iii) substituted or unsubstituted phenyl; ! iv) substituted or unsubstituted heteroaryl; or ! R4 and R5 can be taken together to form a saturated or unsaturated ring having from 5 to 7 atoms; ! said substituents are independently selected from one or more groups selected from C1-C6 linear, branched or cyclic alkyl, halogen, hydroxyl or cyano; ! R6 is a group selected from! i) hydrogen; ! ii) substituted or unsubstituted C1-C6 linear, branched or cyclic alkyl; ! iii) substituted or unsubstituted phenyl and! iv) substituted or unsubstituted heteroaryl; ! R1 is selected from! i) hydrogen; ! ii) C1-C6 linear or branched alkyl; ! iii) substituted or unsubstituted phenyl or! iv) substituted or unsubstituted benzyl; ! R2 is selected from! i) C1-C6 linear or branched alkyl; or! ii) C1-C6 linear or branched alkoxy; ! R3 is hydrogen or C1-C4 linear or branched alkyl. ! 2. The compound according to claim 1, where R has the formula! ! R5 is hydrogen and R4 is hydrogen, substituted or unsubstituted C1-C6 linear, branched or cyclic alkyl, or substituted or unsubstituted phenyl. ! 3. The compound according to claim 1, where R4 is selected from the groups having the formula -CH2F, -CHF2, -CF3, -CH2CF3, -CH2CH2CF3, -CH2Cl, -CH2OH, -CH2CH3, -CH2CH2OH, -CH2CH2CH3, -CH2NH2, - CH2NHCH3, -CH2N (CH3) 2, -CH2NH (CH2CH3), 2,2-difluorocyclopropyl, 2-methoxycyclohexyl, 4-chlorocycle |