http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009101111-A

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filingDate 2007-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2010-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2009101111-A
titleOfInvention GRANULA AND METHOD FOR ITS MANUFACTURE
abstract 1. A pharmaceutical granule consisting of an initial granule and a shell layer outside the original granule with active pharmaceutical ingredients contained in the initial granule and / or in the shell layer, spherical or spherical in shape, with a bulk density of 0.6-1.3 g / ml and a dissolution time of 0.5-5 minutes ! 2. The granule according to claim 1, in which the particle diameter is 700-1500 microns. ! 3. The granule according to claim 2, in which the active pharmaceutical ingredients are selected from the group consisting of any synthetic drugs, traditional Chinese medicine, herbal preparations and / or extracts thereof, in the preferred embodiment, the active pharmaceutical ingredients are traditional Chinese medicine, herbal drugs and / or their extracts. ! 4. The granule according to claim 3, in which the initial granule is made from a pharmaceutically acceptable carrier and / or extract of a traditional Chinese medicine preparation or herbal preparation, and the particle diameter of the initial granule is 200-750 μm. ! 5. The granule according to claim 3, in which the layer of the shell contains an extract of a traditional Chinese medicine or herbal preparation and a pharmaceutically acceptable carrier. ! 6. The granule according to any one of claims 1 to 5, in which the content of a pharmaceutically acceptable carrier relative to the total weight of the granules is 10-60 wt.%, In the preferred embodiment, 20-30 wt.%. ! 7. The granule according to claim 6, in which the granule also has a coating layer, and the content of the coating substance relative to the total weight of the granule is 2-5 wt.%. ! 8. The method of preparation of granules according to any one of claims 1 to 7, consisting of the following steps:! (1) immersion of the original granules in the container ps
priorityDate 2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 30.