http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008152341-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate | 2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2010-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2008152341-A |
titleOfInvention | APPLICATION OF ALLOPURINOL FOR TREATMENT OF PALM-SOIL ERYTHRODESESTHESIA |
abstract | 1. The use of allopurinol or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment or prevention of palm-plantar erythrodysesthesia (PPE) induced by chemotherapy with fluoropyrimidines. ! 2. The use according to claim 1, where the drug is intended for topical application to the skin, preferably for topical application to the hands and feet. ! 3. The use according to claim 2, where the drug is in the form of a cream. ! 4. The use according to any one of claims 1 to 3, where palmar-plantar erythrodysesthesia is induced by 5-fluorouracil chemotherapy. ! 5. The use according to any one of claims 1 to 3, where palmar-plantar erythrodysesthesia is induced by capecitabine chemotherapy. ! 6. The use of allopurinol or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment or prevention of palmar plantar erythrodysesthesia (PPE) induced by pegylated doxorubicin. ! 7. A pharmaceutical composition for topical application to the skin, comprising 1-10% by weight of the total composition of allopurinol or a pharmaceutically acceptable salt thereof, provided that it does not include methylsulfonylmethane or cetomacrogol. ! 8. The pharmaceutical composition according to claim 7, further comprising pyridoxine. ! 9. The pharmaceutical composition according to claim 7 or 8, in the form of a cream, preferably in the form of a hydrophilic cream. ! 10. The pharmaceutical composition according to claim 7 or 8, comprising from about 1 to 8 wt.% By weight of the composition of allopurinol or its pharmaceutically acceptable salt, preferably from about 1 to about 5%, more preferably from about 2 to about 4 wt. |
priorityDate | 2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.