http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008150373-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008150373-A |
| titleOfInvention | OLIGONUCLEOTIDES INFLUENCING THE EXPRESSION OF PHOSPHODYESTERASIS |
| abstract | 1. An oligonucleotide having a base sequence selected from the group consisting of (i) SEQ ID NO: 1-92 and 113-126, as well as (ii) SEQ ID NO: 1-92 and 113-126 containing an insert, deletion or replacement of one base. ! 2. The oligonucleotide according to claim 1, having a base sequence selected from the group consisting of SEQ ID NOs: 1-92 and 113-126. ! 3. The oligonucleotide according to claim 1, having a phosphodiester framework. ! 4. The oligonucleotide according to claim 1, having a phosphorothioate scaffold. ! 5. The oligonucleotide according to claim 4, where at least one nucleotide of the oligonucleotide is a 2'-deoxy-2'-fluoroarabinonucleotide. ! 6. The oligonucleotide according to claim 5, selected from the group consisting of SEQ ID NO: 41-88 and 115-126. ! 7. A pharmaceutical composition comprising at least one oligonucleotide according to any one of claims 1 to 6 in combination with a pharmaceutically acceptable carrier. ! 8. A pharmaceutical composition comprising at least two oligonucleotides according to any one of claims 1 to 6 in combination with a pharmaceutically acceptable carrier. ! 9. The pharmaceutical composition of claim 8, where the first oligonucleotide of at least two oligonucleotides is directed against PDE7A. ! 10. The pharmaceutical composition according to claim 9, where the second oligonucleotide of at least two oligonucleotides is directed against PDE4B and PDE4D. ! 11. The pharmaceutical composition of claim 10, where at least two oligonucleotides are selected from the group consisting of SEQ ID NOS: 41-88 and 115-126. ! 12. The pharmaceutical composition according to claim 11, where at least two oligonucleotides are SEQ ID NO: 2 and SEQ ID NO: 14. ! 13. The pharmaceutical composition according to claim 11, where at least two oligonucleotides are SEQ ID NO: 2 and SEQ ID NO: 24. ! 14. The pharmaceutical composition according to claim 11, where, at least |
| priorityDate | 2006-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.