http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008149511-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 |
| filingDate | 2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008149511-A |
| titleOfInvention | PHARMACEUTICAL PRODUCT FOR INTRAORAL INTRODUCTION OF NICOTINE, INCLUDING TROMETAMOL AS A BUFFER AGENT |
| abstract | 1. Buffered pharmaceutical oral composition containing nicotine, characterized in that it is buffered with at least trometamol. ! 2. The oral composition according to claim 1, buffered in such a way that when the oral composition is orally administered to a subject, the pH of the subject's saliva rises by 0.2-4 pH units. ! 3. The oral composition according to claim 2, buffered in such a way that when the oral composition is administered to a subject, the pH of the subject's saliva increases by 0.5-2 pH units. ! 4. The oral composition according to any one of claims 1 to 3, buffered with trometamol together with a buffer selected from the group consisting of carbonate, such as monocarbonate, bicarbonate or sesquicarbonate, glycinate, phosphate, glycerophosphate, acetate, gluconate or alkali metal citrate, such like sodium or potassium, or ammonium and mixtures thereof. ! 5. The oral composition according to claim 1, where the nicotine in any form is selected from the group consisting of a nicotine salt, nicotine free base form, a nicotine derivative such as a nicotine cation exchanger, a nicotine inclusion complex or nicotine in any form of non-covalent binding, nicotine, bound to zeolites; nicotine bound to cellulose or starch microspheres; and combinations thereof. ! 6. The oral composition according to claim 5, where the nicotine inclusion complex is a cyclodextrin complex, such as β-cyclodextrin. ! 7. The oral composition according to claim 5, where the nicotine cation exchanger is a polyacrylate cation exchanger. ! 8. The oral composition according to claim 5, where the nicotine salt is monotartrate, hydrotartrate, citrate, malate and / or hydrochloride. ! 9. The oral composition according to claim 1, where nicotine in any form is present in an amount of 0.05-8 mg calculated for nicotine in ph |
| priorityDate | 2006-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.