http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008147818-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 |
| filingDate | 2004-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008147818-A |
| titleOfInvention | COMPOSITION FOR A PROTEIN PHARMACEUTICAL DRUG WITHOUT ADDITION OF HUMAN SERUM ALBUMINE (HSA) |
| abstract | 1. Composition for stabilizing protein agents in pharmaceutical preparations, not containing human serum albumin and containing the following components:! a) a surfactant, preferably a non-ionic detergent (tenside), and! b) a mixture of two amino acids, which are aspartic acid (Asp) and asparagine (Asn). ! 2. The composition according to claim 1, where the surfactant is a non-ionic detergent (tenside). ! 3. The composition according to claim 1, additionally containing at least one of the following components:! c) a disaccharide, preferably sucrose (cane sugar), trehalose or lactose,! d) ethylenediaminetetraacetic acid (EDTA), preferably in the form of one of its salts, such as Na4-EDTA. ! 4. The composition according to claim 3, where the disaccharide is sucrose (cane sugar), trehalose or lactose. ! 5. The composition according to claim 1, containing components (a), (b) and (c), components (a), (b) and (d) or components (a), (b), (c) and (g ) ! 6. The composition according to claim 1, where the specified composition is either soluble in aqueous media, or is presented in the form of an aqueous solution. ! 7. A pharmaceutical composition comprising a protein agent and a stabilization composition according to any one of claims 1 to 6. ! 8. The pharmaceutical composition according to claim 7, where the specified pharmaceutical composition is present in the form of a powder freeze-drying or vacuum drying, which is soluble in aqueous media. ! 9. The pharmaceutical composition according to claim 7, wherein said protein agent is a coagulating factor, such as factor VIII (antihemophilic globulin), a cytokine such as interferon, in particular interferon alpha, beta or gamma, an enzyme such as urokinase or streptococ |
| priorityDate | 2003-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.