http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008147658-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C11-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-132 |
| filingDate | 2007-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008147658-A |
| titleOfInvention | PHARMACEUTICAL COMPOSITION BASED ON N1, N4-BIS- (BUTA-1,3-DENYL) BUTAN-1,4-DIAMINE AND WAYS OF ITS APPLICATION |
| abstract | 1. A method of reducing the concentration of reactive oxygen species in the prostate of a man, comprising administering a therapeutic amount of N, N'-bis (2,3-butadienyl) -1,4-butanediamine or a pharmaceutically acceptable salt or solvate thereof. ! 2. The method according to claim 1, in which the active forms of oxygen are one or more compounds selected from the group consisting of hydrogen peroxide, superoxide, hydroxyl radical and nitric oxide. ! 3. A method for the prophylactic treatment of prostate cancer in men, comprising administering a therapeutic amount of N, N'-bis (2,3-butadienyl) -1,4-butanediamine or a pharmaceutically acceptable salt or solvate thereof. ! 4. A method of treating male prostate cancer, comprising administering a therapeutic amount of N, N'-bis (2,3-butadienyl) -1,4-butanediamine or a pharmaceutically acceptable salt or solvate thereof. ! 5. The method according to any one of claims 1 to 4, in which the salt is a hydrochloride. ! 6. The method according to any one of claims 1 to 4, in which the therapeutic amount is in the range of about 1-100 mg / kg body weight, and in which the therapeutic amount is dosed in the range from two times a week to once a day. ! 7. The method according to any one of claims 1 to 4, in which the therapeutic amount is in the range of about 10-40 mg / kg body weight, and in which the therapeutic amount is dosed weekly. ! 8. The method according to any one of claims 1 to 4, in which the therapeutic amount is about 25 mg / kg body weight, and in which the therapeutic amount is dosed twice a week. ! 9. An oral pharmaceutical composition comprising! a therapeutically effective amount of an active pharmaceutical ingredient containing N, N'-bis (2,3-butadienyl) -1,4-butanediam� |
| priorityDate | 2006-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.