http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008145510-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-122 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-03001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 |
| filingDate | 2008-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008145510-A |
| titleOfInvention | COMPOSITIONS AND METHODS FOR DIAGNOSTIC AND TREATMENT OF ASTHMA OR OTHER ALLERGIC OR INFLAMMATORY DISEASES |
| abstract | 1. A method comprising administering a therapeutically effective amount of an agent to a mammal that has an allergic or inflammatory disease, wherein said agent inhibits the activity or expression of a component of the arginine metabolic pathway in tissue affected by the disease, wherein said component is located below the arginase along the metabolic pathway. ! 2. The method according to claim 1, where the disease is a respiratory disease. ! 3. The method of claim 2, wherein the respiratory disease is asthma, chronic airway remodeling, or chronic obstructive pulmonary disease (COPD). ! 4. The method according to claim 3, where the specified agent is able to bind to a component or polynucleotide encoding this component. ! 5. The method according to claim 2, where the specified agent inhibits the expression of the component by RNA interference or antisense mechanism. ! 6. The method according to claim 2, where the specified agent is α-difluoromethylornithine. ! 7. The method according to claim 1, where the mammal is a human. ! 8. The method according to claim 7, where the specified person has asthma or COPD, and the specified component is arginase or a transporter of cationic amino acids, and where the specified agent is able to bind to the specified component or polynucleotide encoding the specified component. ! 9. The method according to claim 1, where the component is selected from the group consisting of ornithine decarboxylase, ornithine aminotransferase, ornithine transcarbamylase, spermidine synthase, spermine synthase and S-adenosylmethionine decarboxylase. ! 10. A method for identifying an agent for the treatment of an allergic or inflammatory disease, comprising:! contacting a molecule with tissue affected by asthma or another allergy |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2588654-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2585229-C2 |
| priorityDate | 2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 138.