http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008143388-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
| filingDate | 2007-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008143388-A |
| titleOfInvention | Hetero compound |
| abstract | 1. The compound of formula (I):! [Chem. 16] ! ! or a pharmaceutically acceptable salt thereof,! where the characters have the following meanings:! Ring A represents! [Chem. 17]! ! X is a single bond, -CH2-, -NR3-, -O-, -S-, -S (= O) -, or -S (= O) 2-,! R1 is —H; halogen; aryl; heteroaryl; (C3-C8) cycloalkyl; (C3-C8) cycloalkenyl; (C3-C8) heterocycloalkyl; or (C1-C6) alkyl or (C2-C6) alkenyl, each of which may contain halogen, -CONH2, aryl or (C3-C8) cycloalkyl as a substituent,! R2 is —CN, —O— (C1-C6) alkyl, —C (= O) H, halogen; or (C1-C6) alkyl, which may be substituted with halogen or -OH,! R3 is —H; where R3 can form morpholino, 1-pyrrolidinyl or 3,4-dehydropiperidin-1-yl, together with R1 and nitrogen,! where, when -X- is a single bond, R1 and R2 may in combination form a 5-membered ring and further contain (C1-C6) alkyl as a substituent,! R4 represents the following ring; ! [Chem. eighteen] ! ! where any one of the bonds from the ring is connected to the oxazole ring! R5 is —H; (C1-C6) alkyl, which may be substituted by at least one group selected from the group consisting of: —CN, —C (= O) NRXRY, —NHRX, —SRX, —S (= O) 2RX, and —ORX, (it is designated as R0- (C1-C6) alkyl); R0- (C1-C6) alkyl-O-; R0- (C1-C6) alkyl-C (= O) -; R0- (C1-C6) alkyl-S (= O) 2-; R0-O- (C1-C6) alkyl-; R0-C (= O) - (C1-C6) alkyl-; R0-S (= O) 2- (C1-C6) alkyl-; (C2-C6) alkenyl-; -C (= O) H; -ORX; -S (= O) 2RX; halogen; = O; -NRXRY; -C (= O) NRXRY! RX and RY may be the same or different from each other and represent -H; or (C1-C6) alkyl, which can be substituted with -OH, NH2, which can be protected with a protecting group or heteroaryl, where RX can form (C3-C8) heterocycloalkyl together with RY and nitrogen,! 2. The compound according to claim 1, which is depicted using the form |
| priorityDate | 2006-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.