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filingDate 2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2010-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2008143202-A
titleOfInvention COMPOSITIONS, METHODS AND KITS USING Adenosine and Inosine in Combinations for Diagnosis and Treatment
abstract 1. A pharmaceutical composition comprising adenosine and inosine in a weight ratio of adenosine: inosine from about 1: 1 to about 1:20, or from about 1: 1 to about 20: 1. ! 2. The pharmaceutical composition according to claim 1, in which the ratio is from about 1: 3 to about 1: 6; in which the ratio is about 1: 4; in which the ratio is about 1: 5; in which the ratio is about 10: 1; or wherein the ratio is from about 7: 1 to about 4: 1; and where, optionally, the pharmaceutical composition is suitable for intravenous, intraatrial or intraarterial infusion. ! 3. The pharmaceutical composition according to claim 1 or 2, in which adenosine and inosine are present in concentrations suitable for intravenous administration at a dosing rate of adenosine of 10-100 μg / kg / min and at a dosing speed of inosine of 10-2000 μg / kg / min; with an adenosine dosing rate of 35-70 mcg / kg / min and an inosine dosing rate of 35-350 mcg / kg / min; or with an adenosine dosing rate of 50-70 mcg / kg / min and an inosine dosing rate of 10-35 mcg / kg / min. ! 4. The pharmaceutical composition according to claim 1 or 2, in which the concentration of adenosine is from about 0.5 to 4 mg / ml; about 3 mg / ml; or about 4 mg / ml; and / or in which the concentration of inosine is from about 0.3 to about 20 mg / ml; from about 0.3 to about 1 mg / ml; or from about 3 to about 4 mg / ml; or about 9 mg / ml; or about 12 mg / ml; or about 15 mg / ml; or from about 18 to about 20 mg / ml. ! 5. A standard dose containing about 7-30 ml or about 200-750 ml of the composition according to any one of claims 1 to 4, wherein the composition is a sterile, non-pyrogenic liquid. ! 6. The combination of hell
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