http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008136316-A
Outgoing Links
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
filingDate | 2007-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2010-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2008136316-A |
titleOfInvention | SODIUM SALT POLYMORPHES N- (4-CHLOR-3METHYL-5-ISOXAZOLYL) -2 {2-METHYL-4, 5- (METHELENDIOXY) Phenylacetyl} THIOPHENE-3-SULFONAMIDE |
abstract | 1. The compound sodium salt of N- (4-chloro-3-methyl-5-isoxazolyl) -2- [2-methyl-4,5- (methylenedioxy) phenylacetyl] thiophene-3-sulfonamide in the form of polymorph A.! 2. The compound according to claim 1, where the amount of polymorph A is more than about 80%. ! 3. The compound according to claim 1, where the amount of polymorph A is more than approximately 95%. ! 4. The compound according to claim 1, where the amount of polymorph A is more than approximately 99%. ! 5. The compound sodium salt of N- (4-chloro-3-methyl-5-isoxazolyl) -2- [2-methyl-4,5- (methylenedioxy) phenylacetyl] thiophene-3-sulfonamide in the form of a mixture of polymorphs A and B, where the ratio of polymorphs A: B is greater than or equal to approximately 80:20. ! 6. The compound according to claim 5, where the ratio of A: B is greater than or equal to approximately 95: 5. ! 7. The compound according to claim 5, where the ratio of A: B is greater than or equal to approximately 99: 1. ! 8. The compound according to any one of claims 1 to 7, where polymorph A is characterized by peaks in the X-ray powder diffraction pattern (XRD) at approximately 22.38 and 23.38 degrees 2-theta. ! 9. The compound according to any one of claims 1 to 7, where polymorph A is characterized by peaks in the pattern of DRLP at approximately 6.72, 15.96, 22.38, 23.38 and 26.22 degrees 2-theta. ! 10. The compound according to any one of claims 1 to 7, where polymorph A is characterized by a peak in the Raman spectra at approximately 1602.1 cm -1. ! 11. The compound according to any one of claims 1 to 7, where polymorph A is characterized by peaks in the Raman spectra at approximately 1697.4, 1602.1, 1489.8 and 1402.2 cm -1. ! 12. The method of producing polymorph A according to any one of claims 1 to 11, comprising the steps! dissolving the sodium salt of N- (4-chloro-3-methyl-5-isoxazolyl) -2- [2-methyl-4,5- (methylenedioxy) phenylacetyl] thiophene-3-sulfonamide in a warm solvent to obtain a saturated solution; and! cooling this |
priorityDate | 2006-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.