http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008134519-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-461 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate | 2007-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008134519-A |
| titleOfInvention | BINDING MOLECULES 3 |
| abstract | 1. A polypeptide binding complex comprising a dimer of a first polypeptide chain and a second polypeptide chain, wherein each polypeptide chain contains an amino terminal VH binding domain; carboxy-terminal binding VH domain; and a dimerization domain, where the dimerization domain preferably lacks CH2-CH3 functionality. ! 2. The polypeptide binding complex according to claim 1, where the dimerization domain is neither engineered nor natural CH2-CH3 domain. ! 3. The polypeptide binding complex according to claim 1 or 2, where the dimerization domain of the first polypeptide chain is different from the dimerization domain of the second polypeptide chain, so that the polypeptide binding complex is a heterodimer. ! 4. The polypeptide binding complex according to claim 1 or 2, where the dimerization domain of the first polypeptide chain is the same as the dimerization domain of the second polypeptide chain, so that the polypeptide binding complex is a homodimer. ! 5. The polypeptide binding complex according to claim 1, where the four VH domains demonstrate the same specificity (tetravalent monospecific complex). ! 6. The polypeptide binding complex according to claim 1, where the amino-terminal binding VH domains demonstrate the same specificity; carboxy-terminal binding VH domains exhibit the same specificity; and the binding specificity of the amino-terminal and carboxy-terminal VH domains is different (a bivalent bispecific complex). ! 7. The polypeptide binding complex according to claim 1, where the amino-terminal binding VH domains show the same specificity; and the carboxy-terminal binding VH domains show different specificity |
| priorityDate | 2006-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458396401 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458393705 |
Total number of triples: 23.