http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008133870-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
| filingDate | 2008-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008133870-A |
| titleOfInvention | FAT CONTROL |
| abstract | 1. A method of regulating fat metabolism or a fat metabolism process in a subject, comprising administering to the subject an effective amount of a compound that inhibits HIF hydroxylase activity, which is a 2-oxoglutarate-dioxygenase mimetic. ! 2. The method according to claim 1, characterized in that the 2-oxoglutarate-dioxygenase mimetic is a substituted heterocyclic carboxamide selected from the group consisting of quinoline-2-carboxamide, isoquinoline-3-carboxamide, phenanthroline, 3-methoxypyridine carbonylglycine, 3 β-hydroxypyridine carbonylglycine, 5-sulfonamidocarbonyl pyridinecarboxylate, pyrimidine and β-carboline. ! 3. The method according to claim 1, characterized in that the compound that inhibits HIF hydroxylase activity is selected from the group consisting of [(7-chloro-3-hydroxy-quinoline-2-carbonyl) amino] -acetic acid, [ (1-chloro-4-hydroxy-isoquinoline-3-carbonyl) amino] acetic acid, [(4-hydroxy-7-phenoxy-isoquinoline-3-carbonyl) amino] acetic acid, 4-oxo-1 , 4-dihydro-[1,10] phenanthroline-3-carboxylic acid, [1-chloro-4-hydroxy-7-methoxy-isoquinoline-3-carbonyl) amino] -acetic acid, [(3-hydroxy-6 -isopropoxy-quinoline-2-carbonyl) amino] -acetic acid, [(3-hydroxy-pyridin-2-carbon l) -amino] -acetic acid methyl ester [(7-benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl) -amino] -acetic acid. ! 4. The method according to claim 1, characterized in that the fat metabolism process is selected from the group consisting of fat absorption, fat transport, fat accumulation, fat processing, fat synthesis and fat utilization. ! 5. A method for achieving fat homeostasis in a subject, comprising administering to the subject an effective amount of a compound that is inhibited |
| priorityDate | 2002-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.