http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008132966-A
Outgoing Links
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-182 |
filingDate | 2007-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2010-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2008132966-A |
titleOfInvention | Cyclohexylpiperazinylmethanone derivatives and their use as histamine H3 receptor modulators |
abstract | 1. Compounds of the general formula! ! where s is 1 or 2; ! R1 is selected from the group consisting of lower alkyl, cycloalkyl, lower cycloalkylalkyl, lower cyanoalkyl, lower alkylsulfonylalkyl and tetrahydropyranyl; ! R1a is hydrogen or lower alkyl; ! R2 is selected from the group consisting of hydrogen, lower alkyl, lower haloalkyl, lower alkoxyalkyl and lower cyanoalkyl; ! R3 is selected from the group consisting of! - (CH2) m-aryl, where m is 0, 1 or 2, and where the aryl ring is unsubstituted or substituted by one, two or three groups independently selected from lower alkyl, halogen, lower haloalkyl, cyano group, lower alkoxy group, lower alkanoyl benzoyl, carbamoyl, lower alkylsulfonyl, lower haloalkylsulfonyl, lower haloalkoxy, lower cycloalkylalkoxy and lower hydroxyalkyl! - (CH2) n-heteroaryl, where n is 0, 1 or 2, and where the heteroaryl ring is unsubstituted or substituted by one or two groups independently selected from lower alkyl, halogen, lower haloalkyl, cyano, lower alkoxy, lower alkanoyl, benzoyl , carbamoyl, lower alkylsulfonyl, lower haloalkylsulfonyl, lower haloalkoxy, lower cycloalkylalkoxy and lower hydroxyalkyl! indanil, 1-oxoindanil,! -CO- (C3-C8) -alkyl,! -CO- (CH2) p-aryl, where p is 0, 1 or 2, and where the aryl ring is unsubstituted or substituted by one, two or three groups independently selected from lower alkyl, halogen, lower halogenated, cyano, lower alkoxy, lower alkanoyl, benzoyl, lower haloalkoxy and lower hydroxyalkyl,! -CO- (CH2) q-hetero |
priorityDate | 2006-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 207.