http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008132871-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 |
| filingDate | 2007-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008132871-A |
| titleOfInvention | TAXOL DERIVATIVES WITH ANTITUMOR ACTIVITY |
| abstract | 1. The compound of formula (I) or its salt:! ! where:! R1 or R2 each independently represents hydrogen, alkyl, halogen-substituted alkyl, or form a group consisting of R1, R2, N and / or O, selected from the groups:! ! Z1 represents hydrogen, hydroxyl, halogen, or C1-C3 alkyl; ! Z2 represents hydrogen, hydroxyl, halogen, or C1-C3 alkyl; ! Z3 is C1-C6 alkyl, C2-C6 alkenyl, C3-C6 cycloalkyl, monocyclic five- or six-membered C6-C10 aryl or C6-C10, wherein said alkyl, alkenyl, alkynyl, cycloalkylaryl or heterocyclic group is optionally substituted with one or more groups selected from the group consisting of halogen, hydroxyl, carboxyl, C1-C3 alkyl, C1-C3 alkoxyl, phenyl, amino, C1-C3 alkylamino, C1-C3 alkoxycarbonyl, C6-C10 aryloxycarbonyl, acyl, amido and acyloxy; ! Z4 is C1-C6 alkyl, C6-C10 aryl and C1-C6 alkoxy, wherein said alkyl, aryl or alkoxy is optionally substituted with one or more groups selected from the group consisting of halogen, hydroxyl, carboxyl, C1-C3 alkyl, C1-C3 alkoxyl, phenyl, amino, C1-C3 alkylamino, C1-C3 alkoxycarbonyl, C6-C10 aryloxycarbonyl, acyl, amido and acyloxy. ! 2. The compound or its salts according to claim 1, where Z1 and Z2 are fluorine. ! 3. The compound or its salts according to claim 1, where Z1 represents hydroxyl, Z2 represents hydrogen. ! 4. The compound or its salts according to claim 1, where Z1 is hydroxyl, Z2 is methyl. ! 5. The compound or its salts according to claim 1, where Z1 is tert-butoxy. ! 6. The compound or its salts according to claim 1, where Z3 is phenyl. ! 7. The compound or its salts according to claim 1, where Z3 is a monocyclic or heterocyclic |
| priorityDate | 2006-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.