http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008130120-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J2200-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-148 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-06 |
| filingDate | 2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008130120-A |
| titleOfInvention | METHOD FOR PRODUCING MEDICINES CONTAINING WAX MATRIX PARTICLES, EXTRUDER FOR USE IN THE METHOD AND MEDICINAL PRODUCT WITH Slow-Release, Containing Cyclostazol |
| abstract | 1. A method of obtaining drug-containing wax matrix granules, including at least one drug and at least one wax, where the method includes the stages:! (i) supplying at least one drug substance and at least one wax to an extruder in which the temperature of the barrel and the temperature of the mold are set higher than the melting point of the at least one wax; and! (ii) simultaneously melting and kneading at least one drug and at least one wax in an extruder, resulting in a molten kneaded mixture of drug and wax, spraying the molten kneaded mixture of drug and wax into a gaseous medium having the temperature is lower than the melting point of the wax, through a spray nozzle directly attached to the mold mounted on the top of the barrel of the extruder, thus forming the mixture into pellets. ! 2. The method of claim 1, wherein the spray nozzle is a one-component liquid nozzle, a pressure nozzle, a two-component liquid nozzle, or a multi-component liquid nozzle. ! 3. The method of claim 1, wherein the extruder is a single screw extruder, a twin screw extruder, or a multi-screw extruder having at least three screws. ! 4. The method of claim 1, wherein the drug-containing wax matrix beads are spherical. ! 5. The method of claim 4, wherein the drug-containing wax matrix granules have an average particle diameter of 1 mm or less. ! 6. Method � |
| priorityDate | 2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.