http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008129683-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 |
| filingDate | 2006-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008129683-A |
| titleOfInvention | IAP INHIBITORS |
| abstract | 1. The compound of formula (I)! ! where X1 and X2, each independently, mean O or S; ! Y is a bond, (CR7R7) n, O or S; ! Z1 is NR8, O, S, SO or SO2; ! Z2, Z3 and Z4 independently mean CQ or N; ! Q is H, halogen, hydroxyl, carboxyl, amino, nitro, cyano, alkyl, carbocycle, heterocycle; where one or more CH2 or CH alkyl groups is optionally replaced by -O-, -S-, -S (O) -, S (O) 2, -N (R8) -, -C (O) -, -C ( O) -NR8-,! -NR8-C (O) -, -SO2-NR8-, -NR8-SO2-, -NR8-C (O) -NR8-, -NR8-C (NH) -NR8-, -NR8-C (NH) -, -C (O) -O- or -OC (O) -; and alkyl, carbocycle and heterocycle are optionally substituted with one or more groups, such as hydroxyl, alkoxy, acyl, halogen, mercapto, oxo, carboxyl, acyl, halogen-substituted alkyl, amino, cyano, nitro, amidino, guanidino, optionally substituted carbocycle or optionally substituted heterocycle; ! R1 is H, OH or alkyl; or R1 and R2 together form a 5-8 membered heterocycle; ! R2 is alkyl, carbocycle, carbocyclylalkyl, heterocycle or heterocyclylalkyl, each of which is optionally substituted with a group such as halogen, hydroxyl, oxo, thion, mercapto, carboxyl, alkyl, haloalkyl, acyl, alkoxy, alkylthio, sulfonyl, amino and nitro, said alkyl, acyl, alkoxy, alkylthio and sulfonyl are optionally substituted with groups such as hydroxy, mercapto, halogen, amino, alkoxy, hydroxyalkoxy and alkoxyalkoxy; ! R3 is H or alkyl optionally substituted with halogen or hydroxyl, or R3 and R4 together form a 3-6 heterocycle; ! R3 ′ is H, or R3 and R3 ′ together form a 3-6 carbocycle; ! R4 and R4 ′ independently mean H, hydroxyl, amino, alkyl, carbocycle, carbocycloalkyl, carbocycloalkyloxy, carbocycloalkyloxycarbonyl, heterocycle, heterocycloalkyl, heterocycloalkyloxy or heterocycloalkyloxy |
| priorityDate | 2005-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.