http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008128454-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2005-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008128454-A |
| titleOfInvention | PHARMACEUTICAL COMPOSITION AND DRUG FORM OF PHENOFIBRATE WITH IMPROVED BIOAVAILABILITY |
| abstract | 1. A pharmaceutical composition comprising microparticles of fenofibrate, polyethylene glycol and polyethylene polypropylene glycol obtained by micronization of a non-mechanical method. ! 2. The pharmaceutical composition according to claim 1, in which microparticles of fenofibrate obtained by micronization of a non-mechanical method are obtained by sublimation micronization. ! 3. The pharmaceutical composition according to claim 2, in which microparticles obtained by micronization of a non-mechanical method are applied to the surface of a set of particles of a pharmaceutically acceptable carrier. ! 4. The pharmaceutical composition according to claim 3, in which upon sublimation micronization, the sublimated carrier is menthol. ! 5. The pharmaceutical composition according to claim 1, in which the polyethylene glycol is a polyethylene glycol 6000.! 6. The pharmaceutical composition according to claim 1, in which polyethylenepolypropylene glycol is poloxamer 407.! 7. The pharmaceutical composition according to claim 6, prepared, in the form of a solid dosage form for oral administration containing from about 15 wt.% To 25 wt.% Fenofibrate, from about 7 wt.% To 13 wt.% Poloxamer 407 and from about 7 wt.% up to 13 wt.% polyethylene glycol 6000.! 8. The solid oral dosage form according to claim 7, further comprising a pharmaceutically acceptable disintegrating agent selected from the following list: crospovidone, croscarmellose sodium, bicarbonate salts, organic carboxylic acids, and any combination of the above components. ! 9. The pharmaceutical composition of claim 8, in which citric acid or tartaric acid is used as the organic carboxylic acid. ! 10. Solid medicine |
| priorityDate | 2005-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.