http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008123219-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 |
| filingDate | 2006-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008123219-A |
| titleOfInvention | Pyridopyrazine derivatives and pharmaceutical compositions and kits containing them and methods for treating or preventing a physiological and / or pathophysiological conditions in mammals by modulating transmission routes Signe ras-Raf-Mek-Erk and PI3K-Akt AND / OR SAPK (OPTIONS) |
| abstract | 1. The use of pyridopyrazine derivatives covered by the general structural formula (I):! ! where the substituents R1, R2, R3, R4 take the following meanings:! R1 and R2 independently mean! (i) hydrogen,! (ii) hydroxyl,! (iii) halogen,! (iv) alkyl, where the alkyl is saturated and contains from 1 to 8 carbon atoms,! (v) unsubstituted or substituted aryl, wherein the aryl is substituted by one or more, same or different substituents selected from the group consisting of F, CI, Br, I, CF3, CN, NH2, NH-alkyl, NH-cycloalkyl, NH-heterocyclyl, NH-aryl, NH-heteroaryl, NH-alkylcycloalkyl, NH-alkylheterocyclyl, NH-alkylaryl, NH-alkylheteroaryl, NH-alkyl-NH2, NH-alkyl-OH, N (alkyl) 2, NHC (O) -alkyl, NHC (O) -cycloalkyl, NHC (O) -heterocyclyl, NHC (O) -aryl, NHC (O) -heteroaryl, NHC (O) -alkylaryl, NHC (O) -alkylheteroaryl, NHSO2-alkyl, N NSO2-cycloalkyl, NHSO2-heterocyclyl, NHSO2-aryl, NHSO2-heteroaryl, NHSO2-alkylaryl, NHSO2-alkylheteroaryl, NO2, SH, S-alkyl, S-aryl, S-g heteroaryl, OH, OCF3, O-alkyl, O-cycloalkyl, O-heterocyclyl, O-aryl, O-heteroaryl, O-alkylcycloalkyl, O-alkylheterocyclyl, O-alkylaryl, O-alkylheteroaryl, O-alkyl-OH, O- (CH2) nO, OS (O) -alkyl, OS (O) -cycloalkyl, OS (O) -heterocyclyl, OS (O) -aryl, OS (O) -heteroaryl, OS (O) -alkylaryl, OS (O ) -alkylheteroaryl, OSO3H, OSO2-alkyl, OSO2-cycloalkyl, OSO2-heterocyclyl, OSO2-aryl, OSO2-heteroaryl, OSO2-alkylaryl, OSO2-alkylheteroaryl, OP (O) (OH) 2, C (O) -alkyl, C (O) -aryl, C (O) -heteroaryl, CO2H, CO2-alkyl, CO2-cycloalkyl, CO2-heterocyclyl, CO2-aryl, CO2-heteroaryl, CO2-alkylcycloalkyl, CO2-alkylheterocyclyl, CO2-alkylaryl, CO2 -alki heteroaryl, C (O) -NH2, C (O) NH-alkyl, C (O) NH-cycloalkyl, C (O) NH-heterocyclyl, C (O) NH-aryl, C (O) NH-heteroaryl, C (O) NH-alkylcycloalkyl, C (O) NH-alkylheterocyclyl, C (O) NH-alkylaryl, C (O) NH-alkylheteroaryl, C (O) N (alkyl) 2, C (O) N (cycloalkyl) 2 , C (O) N (aryl) 2, C (O) N (heteroaryl) 2, SO-alkyl, SO-aryl, SO2-alkyl, SO2-a |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2655604-C2 |
| priorityDate | 2005-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 827.