http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008117298-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008117298-A |
| titleOfInvention | Pyrazolopyrimidines as Protein Kinase Inhibitors |
| abstract | 1. The compound represented by structural formula (I):! ! or a pharmaceutically acceptable salt, solvate, ester or prodrug of a compound of formula (I) wherein! R2 is selected from the group consisting of halogen; -CF3; -CN; -SR6; -NO2; -NR5R6a; -C (O) R6; -S (O2) R7; -S (O2) NR5R10; -N (R5) S (O2) R7; -N (R5) C (O) NR5R10; alkyl; alkenyl; alkynyl; heterocyclyl; heterocyclylalkyl; halogen; haloalkyl; cycloalkyl; aryl; arylalkyl; arylalkenyl; arylalkynyl; heteroarylalkyl; alkynylalkyl; aryl fused to an aryl or heteroaryl group; ; ; and,! where each of the alkyl, alkenyl, alkynyl, heterocyclyl, heterocyclylalkyl, halogenoalkyl, cycloalkyl, aryl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkyl and alkynylalkyl groups, which may or may not be directly substituted above, may be directly or independently presented above fragments that may be the same or different, with each fragment independently selected from the group consisting of halogen, alkyl, aryl, g eteroaryl, cycloalkyl, -CF3, -CN, -OCF3, - (CR11R11) pOR5, -OR5, -NR5R6, - (CR5R11) pNR5R6, -C (O2) R5, -C (O) R5, -C (O) NR5R6, -SR6, -S (O2) R6, -S (O2) NR5R6, -N (R5) S (O2) R7, -C (= N-OH), -N (R5) C (O) R7 and ! —N (R5) C (O) NR5R6, provided that not one of the carbon atoms adjacent to the nitrogen atom of the heterocyclyl ring has an —OR5 substituent; ! R3 is selected from the group consisting of H; -NR5R6a; -OR6b; -SR6; CF3; -C (O) N (R5R6); alkyl; alkenyl, alkynyl; cycloalkyl; aryl; arylalkyl; heterocyclyl; heterocyclylalkyl; heteroaryl; heteroarylalkyl; ! ; ; ; ; ; and,! where each of alkyl, alkynyl; cycloalkyl, aryl, arylalkyl, heterocyclyl, heterocyclylalkyl, heter |
| priorityDate | 2005-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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