http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008117295-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008117295-A |
| titleOfInvention | NEW Pyrazolopyrimidines as Inhibitors of Cyclin-Dependent Kinases |
| abstract | 1. A compound selected from the group consisting of compounds of the formula:! ! ! ! !! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! !! ! ! ! ! and! or their pharmaceutically acceptable salts, solvates, esters or prodrugs. ! 2. The use of at least one compound according to claim 1 or a pharmaceutically acceptable salt, solvate, ester or prodrug thereof for the manufacture of a medicament for inhibiting one or more cyclin-dependent kinases in a patient. ! 3. The use of at least one compound according to claim 1 or a pharmaceutically acceptable salt, solvate, ester or prodrug thereof for the manufacture of a medicament for treating a patient with one or more diseases associated with kinase. ! 4. The use according to claim 3, in which the specified kinase is a cyclin-dependent kinase. ! 5. The use of claim 4, wherein said cyclin-dependent kinase is CDK1, CDK2, or CDK9. ! 6. The use according to claim 5, in which the specified kinase is a CDK2. ! 7. The use according to claim 3, in which the specified kinase is a mitogen-activated protein kinase (MAPK / ERK). ! 8. The use according to claim 3, in which the specified kinase is a kinase-3 glycogen synthase (GSK3beta). ! 9. The use according to claim 3, in which the specified disease is selected from the group consisting of! malignant tumor of the bladder, breast, colon, kidney, liver, lung, small cell lung cancer, non-small cell lung cancer, malignant tumor of the head and neck, esophagus, gall bladder, ovary, pancreas, stomach, cervix, thyroid gland, prostate glands and skin |
| priorityDate | 2005-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 611.