http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008116317-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C249-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C251-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-16 |
| filingDate | 2006-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008116317-A |
| titleOfInvention | SYNTHESIS OF RENIN INHIBITORS USING A CYCLE ADDITION REACTION |
| abstract | 1. The method of obtaining the compounds of formula III! ! in which R is alkyl; ! R1 is alkoxyalkyl; and! R 'is hydrogen, alkyl or arylalkyl; ! or its salt; ! the specified receipt includes (preferably contains)! the interaction of the compounds of formula I! ! in which R and R1 are as defined for the compound of formula III, with glycine of formula II! ! in which R 'is as defined for the compounds of formula III, for the formation of the imino group. ! 2. The compound of formula III! ! in which R is alkyl; ! R1 is alkoxyalkyl; and! R 'is alkyl or arylalkyl, preferably C1-C7-alkyl, C1-C3-alkylphenyl, more preferably C1-C4-alkyl or benzyl, even more preferably ethyl; ! or its salt. ! 3. The compound according to claim 2, which is an ethyl ester of {[1- [4-methoxy-3- (3-methoxypropoxy) phenyl] meth (E) -ylidene] amino} -acetic acid, or a salt thereof . ! 4. The use of the compounds of formula III! ! in which R is hydrogen, alkyl or alkoxyalkyl, preferably C1-C7 alkyl, more preferably methyl; ! R1 is hydrogen, alkyl or alkoxyalkyl, preferably C1-C7-alkoxy-C1-Cc-alkyl, more preferably 3-methoxypropyl; ! R 'is alkyl or arylalkyl, preferably C1-C7-alkyl, C1-C3-alkylphenyl, more preferably C1-C4-alkyl or benzyl, even more preferably ethyl; ! or its salt to obtain renin inhibitors. ! 5. A method of obtaining a compound of formula IV! ! in which R, R1 and R 'are as defined for the compounds of formula III in claims 1-3, where R2 is alkyl, or salts thereof, said preparation includes! the introduction of the compounds of formula III according to claim 2 or 3 in the reaction of cycloaddition with α, β-unsaturated carb |
| priorityDate | 2005-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.