http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008112664-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0012 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2006-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008112664-A |
| titleOfInvention | IMMUNOTHERAPEUTIC TREATMENT |
| abstract | 1. The use of immunotherapy against oxidized low density lipoproteins (LDL) to induce the reverse development of atherosclerotic plaques in individuals. ! 2. The use according to claim 1, where the immunotherapy is directed against the epitope present on oxidized LDL but not on native LDL. ! 3. The use according to claim 1 or 2, where the immunotherapy is directed against at least one oxidized epitope of ApoB-100. ! 4. The use according to claim 3, where the ApoB-100 epitope is selected from the peptides listed in Table 1, or a fragment containing at least 6 consecutive amino acid residues of the peptide listed in Table 1.! 5. The use according to claim 1 or 2, where the immunotherapy is directed against at least one oxidized lipid epitope present on oxidized LDL. ! 6. A method of inducing the reverse development of atherosclerotic plaques in an individual that needs it, including the introduction of an individual:! (a) at least one antibody that selectively binds to the oxidized LDL epitope, or! (b) at least one oxidized LDL epitope. ! 7. The method according to claim 6, where the oxidized LDL epitope comprises an oxidized ApoB-100 epitope. ! 8. The method according to claim 7, where the ApoB-100 epitope is selected from the peptides listed in Table 1, or which is a fragment containing at least 6 consecutive amino acid residues of the peptide listed in Table 1.! 9. The method according to claim 6, where the oxidized LDL epitope comprises an oxidized lipid LDL epitope. ! 10. The method of claim 6, wherein the oxidized LDL epitope comprises an LDL epitope that has been oxidized by exposure to copper or malondialdehyde (MDA). ! 11. The method according to claim 6, where the JAV antibody |
| priorityDate | 2005-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.