http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008110912-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-06 |
| filingDate | 2006-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008110912-A |
| titleOfInvention | DERIVATIVES OF BENZIMIDAZOLE AND THEIR APPLICATION FOR MODULATION OF GABA (GAMMA-AMINOBACYLIC ACID) RECEPTOR COMPLEX |
| abstract | 1. The compound of General formula (I)! ! or its N-oxide, or any of its isomers, or any mixture of its isomers, or its pharmaceutically acceptable salt,! where! Ra, Rb and Rc independently of one another are hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, hydroxy, alkoxy, alkoxyalkyl, formyl, alkylcarbonyl or alkoxyalkylcarbonyl; ! Rd represents an aryl group which is optionally substituted with one or more substituents independently selected from the group consisting of! halogen, hydroxy, R'R''N-, R'R''N-alkyl, R'-SO2-N (R``) -, R '- (C = O) -, R'R''N - (C = O) -, cyano, nitro, trifluoromethyl, trifluoromethoxy, alkoxy, cycloalkoxy, alkyl, cycloalkyl, cycloalkylalkyl, methylenedioxy, ethylenedioxy, alkenyl, alkynyl and - (CR'R '') n-Re; ! where R 'and R "independently of each other represent hydrogen or alkyl; ! n is 0 or 1; and! Re is a heterocyclic ring which may be optionally substituted with halogen, trifluoromethyl, trifluoromethoxy, cyano, nitro, alkyl, hydroxyl or alkoxy. ! 2. The compound according to claim 1, where Ra is hydrogen or alkyl. ! 3. The compound according to claim 1, where Rb represents hydrogen, alkyl, formyl or alkylcarbonyl. ! 4. The compound according to claim 1, where Rc represents hydrogen or alkyl. ! 5. The compound according to any one of claims 1 to 4, where Rd is a possibly substituted phenyl. ! 6. The compound according to any one of claims 1 to 4, where Rd is! ; ! where R2, R3, R4, R5 and R6 independently represent hydrogen, halogen, R'-SO2-N (R``) -, R '- (C = O) -, R'R''N- (C = O) -, cyano, trifluoromethyl, trifluoromethoxy, alkyl or alkoxy, or - (CR'R``) n-Re. ! 7. The compound according to any one of claims 1 to 4, where Rd is phenyl substituted with methylenedioxy. ! 8. The compound according to claim 1, representing |
| priorityDate | 2005-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.