http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008107146-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 |
filingDate | 2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2008107146-A |
titleOfInvention | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATMENT OF DISORDERS OF LIPID METABOLISM |
abstract | 1. The combination of the compounds of formula (I)! ! where ring A is selected from phenyl or thienyl; ! X is selected from —CR2R3—, —O— and —S (O) a—; where a is 0-2; ! Y is selected from -CR4R5-, -O- and -S (O) a-; where a is 0-2; wherein at least one —CR2R3— or —CR4R5— group is present; ! R1 is independently selected from halo, C1-6 alkyl and C1-6 alkoxy; ! b is 0-3; where the values of R1 may be the same or different; ! R2 and R3 are independently selected from hydrogen, hydroxy, C1-6alkyl and C1-6alkoxy; or R2 and R3 together form an oxo group; ! R4 and R5 are independently selected from hydrogen, hydroxy, C1-6 alkyl and C1-6 alkoxy; or R4 and R5 together form an oxo group; ! R6 is independently selected from halo, C1-6alkyl and C1-6alkoxy; ! s is 0-5; where the values of R6 may be the same or different; ! R7 is independently selected from halo, trifluoromethyl, trifluoromethoxy, methyl, ethyl, methoxy and ethoxy; ! d is 0-4; where the values of R7 may be the same or different; ! R9 represents hydrogen or C1-4 alkyl; ! R10 represents hydrogen or C1-4 alkyl; ! R11 and R12 are independently selected from hydrogen, C1-4 alkyl, or carbocyclyl; where R11 and R12 may be independently possibly substituted at the carbon atom with one or more substituents selected from R25; ! R13 represents hydrogen, C1-4 alkyl or carbocyclyl; where R13 may be optionally substituted at the carbon atom with one or more substituents selected from R27; ! R14 is hydrogen, hydroxy, amino, carbamoyl, mercapto, sulfamoyl, C1-10 alkyl, C1-10 alkoxy, C1-10 alkoxycarbonyl, N- (C1-10 alkyl) amino, N, N- (C1-10 alkyl) 2amino, N- (C1-10alkyl) carbamoyl, N, N- (C1-10alkyl) 2-carbamoyl,! C1-10 alkylS (O) a, where a is from 0 to 2, N- (C1-10 alkyl) sulfamoyl, N, N- (C1-10 alkyl) 2sulfamoyl, carboxy or sulfo; where R14 may be optionally substituted at the carbon atom o |
priorityDate | 2002-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.