http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008106057-A

Outgoing Links

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
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filingDate 2006-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2008106057-A
titleOfInvention BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES
abstract 1. The compound of formula I! ! in the form of free substance or in the form of salt, where! R1 is hydrogen or C1-C8 alkyl; ! R2 is phenyl substituted in one position with fluorine and in another position with fluorine, chlorine or C1-C8 alkyl, and R3 and R4 are both hydrogen; ! or R2 is phenyl monosubstituted with chlorine or phenyl, and R3 and R4 are both hydrogen; ! or R2 is phenyl substituted at one, two or three positions with halogen, and one of R3 and R4 is hydrogen, and the other of R3 and R4 is —SO2-NH2, C1-C8 -alkylthio, optionally substituted with C6-C10 aryl, C1-C8 alkylsulfinyl optionally substituted with C6-C10 aryl, C1-C8 alkylsulfonyl optionally substituted with C6-C10 aryl, or a 5- or 6-membered heterocyclic group containing at least one heteroatom in the ring, selected from nitrogen, oxygen and sulfur; ! or R2 is phenyl substituted at one, two or three positions with halogen, R3 is hydrogen, and R4 is fluoro; ! or R2 represents a 5- or 6-membered heterocyclic group containing in the ring at least one heteroatom selected from nitrogen and oxygen, R3 and R4 independently represent hydrogen, halogen, cyano, hydroxy, nitro, carboxy, aminocarbonyl, C1- C8-alkyl, C1-C8-alkenyl, C1-C8-alkynyl, C1-C8-haloalkyl, C1-C8 -alkylthio, optionally substituted with C6-C10-aryl, C1-C8-alkylsulfinyl, optionally substituted with C6-C10-aryl, C1-C8-alkylsulfonyl optionally substituted with C6-C10-aryl, C1-C8-alkoxy, C1-C8-haloalkoxy, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C8- lkil, C3-C8-cycloalkyloxy, -CO-NR5R6, -NH-SO2R7, -NH-COH, -SO2NH2, or a 5- or 6-membered heterocyclic
priorityDate 2005-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 57.