http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008102730-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
filingDate | 2006-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2008102730-A |
titleOfInvention | USE OF UROKINASE INHIBITORS FOR THE TREATMENT AND / OR PREVENTION OF NEUROPATOLOGICAL DISEASES |
abstract | 1. The use of an urokinase inhibitor of the general formula I! ! in which Ar denotes an aromatic or heteroaromatic cyclic system,! E stands for! or ! or Ar and E together form a radical! or ! where Z may be O, NH or C = O, and X4 may be C = O, NH or CH2, and W may be N, CR3 or CR6, and X5 may be CH, CR3, CR6 or N, ! B is -SO2-, -CR3 2-, -NR3- or -NH-,! X1 denotes NR13R4, OR3, SR3, COOR3, CONR3R4 or COR5,! R1 is H, an optionally substituted alkyl, alkenyl, alkynyl, aryl, heteroaryl radical or COOR3, CONR3R4 or COR5,! R2 is halogen, C (R6) 3, C2 (R6) 5, OC (R6) 3 or OC2 (R6) 5,! R3 is H or any organic radical,! R13 is a group of general formula (IIa) or (IIb)! ! ! X2 is NH, NR4, O or S,! X3 is NH, NR4, O, S, CO, COO, CONH or CONR4,! Y is C (R8) 2, NH or NR3,! R4 is H or a branched or unbranched optionally substituted alkyl, alkenyl or alkynyl radical,! R5 is H, alkyl, alkenyl, alkynyl, carboxyalkyl, carboxyalkenyl, carboxylalkynyl, carboxyaryl, carboxyheteroaryl, - (CO) NR3R4 or -COO-R3, where the alkyl, aryl and heteroaryl radicals may be optionally substituted! R6 in each case is independently H or halogen, and in particular F,! R7 is H or an optionally substituted alkyl, alkenyl, alkynyl, aryl or heteroaryl radical or COR9,! R8 in each case represents, independently, H or a branched or unbranched optionally substituted alkyl, alkenyl, alkynyl, aryl, heteroaryl, aralkyl, alkylaryl, heteroalkyl radical and / or substituted or un |
priorityDate | 2005-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 250.