http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2008100045-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 |
| filingDate | 2006-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2008100045-A |
| titleOfInvention | ACTIVITY INHIBITORS Akt |
| abstract | 1. The compound of formula A:! ! in which E, F, G, H, I, J, K, L and M are independently selected from C or N, where each E, F, G, H, I, J, K, L and M is optionally substituted with R1; ! a is 0 or 1; b is 0 or 1; m is 0, 1 or 2; p is independently 0, 1, 2, 3, 4, or 5; ! ring Z is selected from (C3-C8) cycloalkyl, aryl, heteroaryl and heterocyclyl; ! R1 is selected from the oxo group, (C = O) aOb (C1-C10) alkyl, (C = O) aOb-aryl, (C = O) aOb (C2-C10) alkenyl, (C = O) aOb (C2-C10 ) alkynyl, CO2H, halogen, OH, Ob (C1-C6) perfluoroalkyl, (C = O) aNR7R8, CN, (C = O) aOb (C3-C8) cycloalkyl, S (O) mNR7R8, SH, S (O ) m- (C1-C10) alkyl and (C = O) aOb-heterocyclyl, wherein said alkyl, aryl, alkenyl, alkynyl, cycloalkyl and heterocyclyl are optionally substituted with one or more substituents selected from R6; ! R2 is independently selected from the oxo group, (C = O) aOb (C1-C10) alkyl, (C = O) aOb-aryl, (C = O) aOb (C2-C10) alkenyl, (C = O) aOb (C2- C10) alkynyl, CO2H, halogen, OH, Ob (C1-C6) perfluoroalkyl, (C = O) aNR7R8, CN, (C = O) aOb (C3-C8) cycloalkyl, SH, S (O) mNR7R8, S ( O) m- (C1-C10) alkyl and (C = O) aOb-heterocyclyl, wherein said alkyl, aryl, alkenyl, alkynyl, cycloalkyl and heterocyclyl are optionally substituted with one or more substituents selected from R6; ! R3 is independently selected from an oxo group, (C = O) aOb (C1-C10) alkyl, (C = O) aOb-aryl, (C = O) aOb (C2-C10) alkenyl, (C = O) aOb (C2- C10) alkynyl, CO2H, halogen, OH, Ob (C1-C6) perfluoroalkyl, (C = O) aNR7R8, CN, (C = O) aOb (C3-C8) cycloalkyl, S (O) mNR7R8, SH, S ( O) m- (C1-C10) alkyl, (C1-C6) alkylheterocyclyl and (C = O) aOb-heterocyclyl, wherein said alkyl, aryl, alkenyl, alkynyl, cycloalkyl and heterocyclyl are optionally substituted with one or more substituents selected from R6; ! R6 is (C = O) aObC1-C10-alkyl, (C = O) aOb-aryl, C2-C10-alkenyl, C2-C10-alkynyl, (C = O) aOb-heterocyclyl, CO2H, halogen, CN, OH , ObC1-C6-perfluoroalkyl, Oa (C = O) bNR7R8, oxo, CHO, (N = O) R7R8, S (O) mNR7R8, SH, S (O) m- (C1-C10) alkyl or (C = O) aObC3-C8-cycloalkyl, wherein said alkyl, aryl, alkenyl, alkynyl, heteroc |
| priorityDate | 2005-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 421.