| abstract |
1. A method for producing 4- (3,4-dichlorophenoxy) piperidine, comprising the steps of:! a. reacting 4-hydroxypiperidine with a suitable base in a suitable solvent at room temperature and! b. heating the mixture thus obtained and 1,2-dichloro-4-fluorobenzene at a temperature of 50-90 ° C. or at the boiling point of the solvent used. ! 2. The method according to claim 1, where a suitable base is a C1-10 alkali metal alkoxide. ! 3. The method according to claim 2, where the alkali metal is sodium or potassium. ! 4. The method according to claim 2, where a suitable base is a C4-10-tertiary alkali metal alkoxide. ! 5. The method according to claim 4, where a suitable base is potassium tert-butoxide or 3,7-dimethyl-3-potassium octanooxide. ! 6. The method according to any one of claims 1 to 5, where the solvent is ether, an aromatic solvent or a mixture of these solvents. |