http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2007146706-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-313 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate | 2006-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2007146706-A |
| titleOfInvention | OLIGONUCLEOTIDE OR ITS FUNCTIONAL Homologue CONTAINING ITS COMPOSITION AND METHOD FOR TREATING A B-CELL TUMOR |
| abstract | 1. A method of treating a B-cell tumor in a mammalian subject, comprising administering to a subject who needs treatment a therapeutically effective amount of a pharmaceutical composition comprising an oligonucleotide that has any of the sequences of SEQ ID NO: 1-9. ! 2. The method according to claim 1, providing for the induction of apoptosis of B-cell tumor cells. ! 3. The method according to claim 1, comprising increasing the expression of CD40 on B-cell tumor cells. ! 4. The method according to claim 1, where the specified method provides for the stimulation of the formation of IL-10 by B-cell tumor cells. ! 5. The method according to claim 1, where the specified B-cell tumor is Β-cell leukemia, Β-cell lymphoma or myeloma. ! 6. The method according to claim 5, where the specified Β-cell leukemia is B-cell chronic lymphocytic leukemia or B-cell acute lymphocytic leukemia. ! 7. The method according to claim 5, where the specified Β-cell lymphoma is a lymphoma from small lymphocytes. ! 8. The method according to claim 1, wherein said mammalian subject is a human subject. ! 9. The method according to claim 1, where the specified pharmaceutical composition is administered enterally, parenterally or topically, or by inhalation. ! 10. A method of inducing apoptosis of B-cell tumor cells, comprising contacting said B-cell tumor cells with a composition comprising an oligonucleotide having any of the sequences of SEQ ID NO: 1-9. ! 11. A method of increasing expression of CD40 on Β-cell tumor cells, comprising contacting said B-cell tumor cells with a composition comprising an oligonucleotide having any of the sequences of SEQ ID NO: 1-9. ! 12. Method of inducing education |
| priorityDate | 2005-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.