http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2007146270-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-00 |
| filingDate | 2007-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2007146270-A |
| titleOfInvention | HETEROCYCLIC INHIBITORS OF THE HH SIGNAL CASCADE, MEDICINAL COMPOSITIONS ON THE BASIS AND METHOD FOR TREATING DISEASES CONNECTED WITH ABBERANT HH SIGNAL SYSTEM ACTIVITY |
| abstract | 1. Derivatives of 2,6-dihydro-7H-pyrazolo [3,4-d] pyridazin-7-ones of the general formula I! ! in which n can take values 0, 1, 2 and 3; ! R1 is H, an inert substituent, an NH-protective or electrophilic substituent; ! R2, R5 are H or lower alkyl; ! R3 is H or an inert substituent; ! R4 is H or an inert substituent; the substituents R4a and R4b may together form an optionally substituted carbo or heterocycle, with the R4a-N-R4b moiety being optionally substituted azaheterocycles (e.g. pyrrolidine, piperidine, piperazine, homopiperazine, morpholine, thiomorpholine and others). ! 2. Derivatives of 1,4-dihydropyrazolo [3,4-b] thiazin-5 (6H) -ones of general formula II! ! in which m can take values 0, 1, 2 and 3; ! R6 is H, an inert, NH-protective or electrophilic substituent; ! R7 is H or an inert substituent; ! R8 represents H or an inert substituent; ! R9 is H or an inert substituent; substituents R9a and R9b may together form an optionally substituted carbo or heterocycle, wherein the R9a-N-R9b moiety may be optionally substituted azaheterocycles (e.g., pyrrolidine, piperidine, piperazine, homopiperazine, morpholine, thiomorpholine and others). ! 3. Derivatives of 4-imidazo [1,2-a] pyridin-2-yl-anilines of the general formula III! ! wherein: ! R10 represents H or an inert substituent; ! R11 represents H or an inert substituent; ! R12 represents H, halogen, CF3, CF3O, CN, a nitro group or an inert substituent. ! 4. Derivatives of 4-imidazo [1,2-a] pyrimidin-2-yl-anilines of the general formula IV! ! wherein: ! R13 represents H or an inert substituent; ! R14 represents H, halogen, CF3, CF3O, CN, a nitro group or an inert substituent |
| priorityDate | 2007-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 409.