http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2007143325-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D267-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-553 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
filingDate | 2006-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2007143325-A |
titleOfInvention | MEDICINE FOR Xanthoma |
abstract | 1. A means of preventing and / or treating xanthomatosis, or physical dysfunction, or cosmetic disorder that results from the formation of xanthomas, including a compound having an inhibitory effect on squalene synthase, its prodrug, or its salt. ! 2. The tool according to claim 1, which is a prophylactic and / or therapeutic agent for xanthomatosis. ! 3. The tool according to claim 1, where the compound having an inhibitory effect on squalene synthase is a compound of the formula! ! where R1 represents hydrogen or an optionally substituted hydrocarbon group; R 2 and R 3 are the same or different and represent a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X 'represents an optionally esterified carboxyl group, an optionally substituted carbamoyl group, an optionally substituted hydroxyl group, an optionally substituted amino group or a group consisting of an optionally substituted heterocyclic residue containing a hydrogen atom that can be deprotonated; ring A is an optionally substituted benzene ring or an optionally substituted heterocycle; ring J ′ is a 7-8 membered heterocycle containing three or less heteroatoms as ring-forming atoms, and ring J ′ may contain, in addition to R1, R2, R3 and X ′, an additional substituent. ! 4. The tool according to claim 1, where the compound having an inhibitory effect on squalene synthase is a compound of the formula! ! where R1 is optionally substituted |
priorityDate | 2005-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.