http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2007116157-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 |
filingDate | 2005-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2007116157-A |
titleOfInvention | STABLE PRODUCTS OF INSULINOTROPIC PEPTIDES |
abstract | 1. A shelf stable pharmaceutical composition comprising an insulinotropic peptide, a pharmaceutically acceptable preservative, poloxamer or polysorbate 20 surfactant in a concentration of from about 10 to about 400 mg / L and, optionally, a pharmaceutically acceptable tonicity modifier, where the pH of the composition is in the range from about 7.0 to about 8.5.2. The pharmaceutical composition according to claim 1, characterized in that the concentration of surfactant is from about 20 to about 300 mg / L or from about 50 to about 200 mg / L. The pharmaceutical composition according to any one of claims 1 and 2, characterized in that the surfactant is poloxamer 188.4. The pharmaceutical composition according to any one of claims 1 and 2, characterized in that the surfactant is selected from the group consisting of Poloxamer 407, Poloxamer 124, Poloxamer 181, Poloxamer 182, Poloxamer 237, Poloxamer 331 and Poloxamer 338.5. The pharmaceutical composition according to any one of claims 1 and 2, characterized in that the surfactant is polysorbate 20.6. A composition comprising an insulinotropic peptide and an alkyl polyglucoside, and optionally a pharmaceutically acceptable tonicity modifier. 7. The composition according to claim 6, characterized in that the pH of the composition is in the range from about 7.0 to about 8.5.8. Composition according to any one of claims 6 and 7, characterized in that the alkyl polyglucoside is in a concentration of from about 10 mg / L, or from about 1000 mg / L, or from about 10 to about 15000 mg / L, or from about 1000 to |
priorityDate | 2004-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.