http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2007115639-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 2005-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2007115639-A |
| titleOfInvention | Quinoline as an allosteric enhancer of GABA-B receptors |
| abstract | 1. Compounds of Formula I where R 1 is hydrogen, C 1-6 alkyl, C 1-4 haloalkyl, di (C 2 C) alkylamino, 5-6 membered heterocycloalkyl; R 1 is C 1-6 alkyl, aryl, C 1-4 alkoxy ( C-C) alkyl, C-Caloalkyl or C-Cycloalkyl; R, R each independently represent hydrogen, halogen, hydroxy, C-Calkoxy, C-Caloalkoxy, di (C-C) alkylamino, C-Cialkylsulfonyl, or 5- or 6-membered heterocycloalkyl; R is hydrogen, halogen, C-Cialkyl, C-Cialkoxy, Ci-Ci-haloalkoxy, or aryloxy, or is -NRR where Ri and Ri are Ci-Cialkyl, or Ri R may, together with the nitrogen atom to which they are attached, form a 4-7 membered heterocycloalkyl group which may be substituted by one or more substituent (s) selected from the group consisting of halogen, C-C1-6 alkyl, C-Salkoxy, hydroxy, phenyl and di (C-C) alkylamino; R represents hydrogen or together with R may form a 5- or 6-membered heterocycloalkyl group which may be substituted by one or more halogen; and their pharmaceutically acceptable acid addition salts, except following with distinctions: 1- (6-chloro-2-methyl-4-phenyl-quinolin-3-yl) -ethanone, 1- (6-bromo-4-phenyl-2-piperidin-1-yl-quinolin-3-yl ) -ethanone, 1- [4- (4-chloro-phenyl) -2-methyl-quinolin-3-yl] -ethanone, 1- (6-bromo-2-methyl-4-phenyl-quinolin-3-yl ) -ethanone, 1- (2,6-dimethyl-4-phenyl-quinolin-3-yl) -ethanone, 1- (2-methyl-4-phenyl-6-trifluoromethoxy-quinolin-3-yl) -ethanone, phenyl- (4-phenyl-quinolin-3-yl) -methanone, phenyl- (4-phenyl-quinolin-3-yl) - (2,4,6-trimethyl-phenyl) methanone, (2-methyl-4 -phenyl-quinolin-3-yl) -phenyl-methanone, 1- (2-methyl-4-phenyl-quinolin-3-yl) -ethanone, 1- (6-chloro-2-methyl-4-phenyl-quinoline -3-yl) ethanone, 1- (4-phenyl-quinolin-3-yl) -ethanone, 1- (6-chloro-4-phenyl-quinolin-3-yl) -ethanone, 1- |
| priorityDate | 2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 199.