http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2006147277-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D253-06 |
| filingDate | 2005-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2006147277-A |
| titleOfInvention | METHOD FOR PRODUCING 5- (2-HYDROXYETHYL) -3, 5-DIOXO-4, 5-DIHYDRO-3H- (1, 2, 4) TRIAZIN-2-YL) BENZAMIDE DERIVATIVES WITH RELIABLE RELIEF TO THE RELIEF TO THE RELIEF TO THE RELIEF TO THE RELIEF TO P2 NOT SUBSTITUTED IN REGULATION 4, WITH OXYRAN IN THE PRESENCE OF LEWIS ACID |
| abstract | 1. A process for preparing a compound of formula I or a pharmaceutically acceptable salt thereof, wherein R is (CC) alkyl optionally substituted with (CC) cycloalkyl, phenyl, naphthyl, 5 or 6 membered heterocycloalkyl, or 5 or 6 membered heteroaryl, wherein each of said (CC) alkyl, (CC) cycloalkyl, phenyl, naphthyl, 5 or 6 membered heterocycloalkyl, or 5 or 6 membered heteroaryl optionally substituted with one to three substituents independently selected from the group consisting of hydroxy, halogen, CN -, (CC) alkyl, HO (CC) alkyl, (CC) alkyl-NH (C = O) -, NH (C = O) -, (CC) alkox or (CC) cycloalkyl; R represents hydrogen, halogen, —CN, or (CC) alkyl, wherein said (CC) alkyl is optionally substituted with one to three substituents independently selected from the group consisting of halogen, hydroxy, amino, —CN , (CC) alkyl, (CC) alkoxy, -CF, CFO -, (CC) alkyl-NH-, [(CC) alkyl] -N -, (CC) alkyl-S -, (CC) alkyl- (S = O) -, (CC) alkyl- (SO) -, (CC) alkyl-O- (C = O) -, formyl, (CC) alkyl- (C = O) - and (CC) cycloalkyl; where R is independent selected from the group consisting of hydrogen, halogen, hydroxy, —CN, HO- (CC) alkyl, (CC) alkyl, optionally substituted with one to three fluorine atoms, (CC) alkoxy, optionally substituted one to three fluorine atoms, HOC -, (CC) alkyl-O- (C = O) -, RRN (OS) -, (CC) alkyl- (OS) -NH -, (CC) alkyl-OS- [ (CC) alkyl-N] -, RRN (C = O) -, RRN (CH) -, phenyl, naphthyl, (CC) cycloalkyl, 5- or 6-membered heteroaryl, 5 or 6-membered heterocycloalkyl, phenyl-O -, naphthyl-O -, (CC) cycloalkyl-O-, 5- or 6-membered heteroaryloxy and 5 or 6-membered heterocycloalkyl-O- and R are —CH — C (RR) —OH, where R and R are independently selected from the group consisting of: hydrogen, phenyl and (CC) alkyl optionally substituted with one to three halogens, hydroxy, -CN, (CC) alkoxy-, ((CC) alkyl) -N -, (CC) alkyl- (C = O ) -, (CC) cycloalkyl- (C = O) -, 5 or 6 membered |
| priorityDate | 2004-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.