http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2006146666-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3069 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate | 2005-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2006146666-A |
| titleOfInvention | ANTIBODIES AND RELATED MOLECULES BINDING PSCA PROTEINS |
| abstract | 1. A monoclonal antibody or fragment thereof containing an antigen binding site that specifically binds to a prostate stem cell antigen protein (PSCA) (SEQ ID NO: 2), where inventory number PTA-6698, PTA-6703, PTA-6699 is assigned, PTA-6700 or PTA-7602 in the American Type Culture Collection (A.T.S.C.). 2. The antibody or fragment thereof according to claim 1, wherein the monoclonal antibody comprises a heavy chain variable region (VH) of SEQ ID NO: 22 and a light chain variable region (VL) of SEQ ID NO: 23; VH SEQ ID NO: 17 and VL SEQ ID NO: 18; VH SEQ ID NO: 13 and VL SEQ ID NO: 14; VH SEQ ID NO: 15 and VL SEQ ID NO: 16; VH SEQ ID NO: 19 and VL SEQ ID NO: 20 or VH SEQ ID NO: 28 and VL SEQ ID NO: 29.3. An antibody or fragment thereof according to claim 1, wherein the fragment is a Fab, F (ab '), Fv or Sfv fragment. An antibody or fragment thereof according to any one of claims 1, 2 or 3, wherein the antibody or fragment thereof is conjugated to a detectable marker, toxin, therapeutic agent or chemotherapeutic agent. The antibody or fragment thereof according to claim 4, wherein the detectable marker is a radioisotope, a metal chelator, an enzyme, a fluorescent compound, a bioluminescent compound or a chemiluminescent compound. The antibody or fragment thereof according to claim 5, wherein the radioisotope comprises Bi, I, In, Y, Re, At, I, Re, Sm, Bi, P or Lu. The antibody or fragment thereof according to claim 4, wherein the toxin comprises ricin, ricin A domain, doxorubicin, daunorubicin, meytansinoid, taxol, ethidium bromide, mitomycin, etoposide, tenoposide, vincristine, vinblastine, colchicine, digidroksiantratsindion, actinomycin, diphtheria toxin, exotoxin A Pseudomonas (PE), PE40, abrin, domain A of abrine, domain A of modecin, alpha-sarcin, gelonin, mitogellin, retrictocin, phenomycin, enomycin, curicin, crotin, calicheamicin, an inhibitor of Saponaria officinalis, glucocorticoid, and |
| priorityDate | 2004-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.