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filingDate 1988-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1993-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c7f765cb1f345891e60994186f86846
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publicationDate 1993-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2002744-C1
titleOfInvention Method of synthesis of 1-substituted 6-fluoro-4-oxo-7-(1- piperazinyl)-1,4- -dihydroquinoline-3-carboxylic acid
abstract SUMMARY OF THE INVENTION Product of UNIVERSITY: UNO Where R is cpd, cyclopropyl or hydroxyethyl Reagent 11 is substituted 6-fluoro-4-oxo-7- {4-carboethoxy-b-fluoro-4-oxo-7- (4-carboethoxy -1-piperazinyl) -1,4-dihydroquinoline-3-carboxylic acid Reagent 2. Alkaline reagent - a mixture of ethanol and an aqueous base solution (KOH). Reaction conditions: boiling the reaction mixture. Yield 50 - 96%. 2 zlfs.
priorityDate 1987-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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