| abstract |
Usage: the invention relates to the pharmaceutical industry and relates to the production of lyophilized anthracycline glycoside powder. The goal is to increase the absorption of the target product. SUMMARY OF THE INVENTION A method for preparing a lyophilized anthracycline glycoside powder is provided. selected from doxorubicin. 4-epi-doxorbicin, 41-deoxydoxorubicin, daunorubicin and 41-demethoxy-daunorubicin and their hydrochlorides and dissolving them in a solubilizing solution, such as a solution of para-hydroxybenzoic acid, methyl ester of para-hydroxybenzoic acid, steam -aminobenzoic acid, salicylic acid, 3-methyl-4-chlorophenol, 3,5-dimethyl-4-chlorophenol, glycine, cysteine, phenylalanine or proline in water for use in injections, after clarification of the solution, it is filtered under sterile conditions x and frozen to a temperature of (-40) to (-50) ° C for 4-6 hours, then dried at 40-50 ° C for 6-7 hours |