| abstract |
Use: as an anti-AIDS drug. The inventive product () -4- (6-amino-9H-purin-9-yl) - tetrahydro-2-furan-methanol, BP CioHi3Ns02, so pl. 183-185 ° C, 50% yield; | (3R-cis) -2-amino-1 .E-dihydro-E-Ptetrahydro | 5- {oxymethyl) -3-furanyl 6 N-purin-6-OH, BP CloHiaNsOs, yield 40%, mp. 229-230 ° C. Reagent 1: (2P-trans) -tetrahydro-4 (4-methylphenyl) sulfonyl) oxy-2-furanmethanol. Reagent 2: adenine or guanine. Reaction conditions: in dimethylformamide medium in the presence of 18-crown-b and potassium carbonate. (L C |