http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-1799382-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1989-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f5004f69efae7f15e9433ee069d859 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c87df7ffe20c49156cd85fd94944736 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d80bae8789b09e9d64bef7f64aeb1c82 |
| publicationDate | 1993-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-1799382-C |
| titleOfInvention | Method of substituted pyrrols or theirs pharmaceutically acceptable salts synthesis |
| abstract | SUMMARY OF THE INVENTION: substituted pyrroles of formula I ... n 0 "N —O. d. R, Teg-g 3 1 N JYA-f W c, cng where RT- H, lower alkyl, possibly substituted with an OH group; R2 and Pz — H, halogen, lower alkyl, lower alkylthio group, NHa; - N.CH, R - CbH3, provided that Ri, R2, R3, R4-H, CH3, or - (CHg) p - X. p 2-6, X - H, OH, an azido group, halogen, aminocarbo- nyl, carboxyl, lower alkoxycarbonyl, lower alkylsulfonyloxy, CN, isothiocyanato, 1 - pyridinium, amidino. lower alkylsulfinyl, lower alkylsulfinyl, mercaptb, possibly substituted by lower alkyl, hydroxy lower alkyl, lower alkyl carbonyl, imidazol-2-yl, imidazolin-2-yl, 1-methyltetrazol-5-yl, pyridin-1-oxide -yl or amidine, or-NH2, possibly substituted 1-3 times with lower alkyl or 1 time with lower aminoalkyl, nitripyridin-2-yl, pyrmidin-2-yl, phenylsulfo, lower alkylsulfo, phenylcarbonyl, imidazol-1-yl -carbonyl, lower alkylcarbonyl, aminocarbonyl, amidino, (4-benzyloxyphenyl) iminocarbonyl,. (4-hydroxyphenyl) iminocarbonyl, amino nitroiminocarbonyl, aminothiocarbonyl, amino cyaniminocarbonyl, methylamino cyaniminocarbonyl, dimethylaminocyaniminocarbonyl, methyl and animocarbonyl, - 1-amino-2-nitro-2-nitro-1-1-nitro. rovinyl group, or their pharmaceutical. sky acceptable salts. Reagent 1: compound I, where O is contained in cycle A instead of N. Reagent 2: MH 3 or (CHabSlfcNH in methanol. Reaction conditions: respectively, under pressure in DMF and water or in toluene or chloroform. If necessary, the product is transferred to the corresponding modified; derivative and isolated in its free form or in the form of salt. 2 tab. |
| priorityDate | 1988-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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