| abstract |
Usage: in medicine, since the products exhibit pharmacological activity - antiplatelet. Essence: A method of producing new dmRphenylethylene derivatives of the general formula n Ri-CeH4C (n R2-CeH4) C / C (СН2 / СН2) pCOOBz, where Ri, Ra - each means 4-methoxy group, Pz-hydrogen or Ci-Ce- alkyl, n-integer 1-3. Reagent 1: n-CeH4COC6H4R2-n. Reagent 2: Ha1 / CN / CH2 / nCOOR3. The reaction conditions of reagent 1 are reacted with reagent 2 in the presence of zinc to give a product of the general formula: (p-CbH4XOH) With CH (CNXCH2) nCOOR3 which is dehydrated, isolated or, if necessary, hydrolyzed to the corresponding acid. 2 tab. ate with |